BME562

Engineering biological systems emphasizing synthetic biology and the application of biological/chemical principles to the design of new biomolecules and cellular pathways. Review of primary scientific literature, highlighting contemporary research in this area, including artificial amino and nucleic acids, gene regulatory systems, directed molecular evolution, recombinant antibodies, novel biosynthesis pathways, cell communication, and the design of minimal organisms. Topics are presented with applications such as drug design, discovery, productions, regenerative medicine, and bioremediation. Prerequisite: Biomedical Engineering 244L. Organic chemistry or biochemistry suggested. Instructor consent required.